Photodynamic Inactivation of Cariogenic Pathogens Using Curcumin as Photosensitizer
نویسندگان
چکیده
منابع مشابه
Photodynamic effects of curcumin against cariogenic pathogens.
BACKGROUND DATA The presence of Streptococcus mutans and Lactobacillus acidophilus in dental structure is an indicator of a cariogenic biofilm. Photodynamic therapy is a technique that involves the activation of photosensitizers by light in the presence of oxygen, resulting in the production of reactive radicals capable of inducing cell death. Reduction of bacteria levels can provide additional...
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Root canal disinfection is one of the main factors governing success of endodontic therapy. Antimicrobial photodynamic therapy (aPDT) is presented as a promising antimicrobial therapy that can eliminate microbiota present in infected root canal systems. In this study, a series of experiments investigated the effects of aPDT on cell viability and biofilm degradation ability of endopathogenic mic...
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1. Photodynamic therapy could be an alternative treatment for highly prevalent local antibiotic-resistant pathogens. 2. Photodynamic inactivation using toluidine blue O was observed on both reference strains and clinical samples, including methicillin-resistant Staphylococcus aureus, e x t e n d e d s p e c t r u m β l a c t a m a s e – p r o d u c i n g Escherichia coli and Klebsiella pneumoni...
متن کاملFolic acid conjugated ferritins as photosensitizer carriers for photodynamic therapy.
We coupled folic acid as a tumour targeting ligand to the surface of ferritins and loaded them with ZnF16Pc. The resulting nanoconjugates can efficiently hone in on 4T1 tumours in vivo, and, with photoirradiation, leading to suppressed tumour growth and tumour metastasis.
متن کاملPolycationic photosensitizer conjugates: effects of chain length and Gram classification on the photodynamic inactivation of bacteria.
OBJECTIVES We have shown previously that a polycationic conjugate between poly-L-lysine and the photosensitizer chlorin(e6) was effective in photodynamic inactivation (PDI) of both Gram-positive and Gram-negative bacteria. In this report we explore the relationship between the size of the polylysine chain and its effectiveness for mediating the killing of Gram-negative and Gram-positive bacteri...
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ژورنال
عنوان ژورنال: Photomedicine and Laser Surgery
سال: 2017
ISSN: 1557-8550
DOI: 10.1089/pho.2016.4156